Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28604148 | 0.86 | — | — | |
| SCHEMBL27755242 | 0.73 | FFAR3 (0.36) | — | |
| SCHEMBL27755360 | 0.71 | DGAT1 (0.36) | — | |
| SCHEMBL10477604 | 0.71 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL10477606 | 0.71 | SMN1; SMN2 (0.40) | SMN1; SMN2 | |
| SCHEMBL19699898 | 0.70 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL17558776 | 0.69 | TSHR (0.36) | — | |
| SCHEMBL23009421 | 0.69 | CYP2C19 (0.34) | SMN1; SMN2 | |
| SCHEMBL10477627 | 0.69 | — | — | |
| SCHEMBL10477629 | 0.69 | PPARD (0.39) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074859-B | Cyclohexylethyl substituted diaza-and triaza-tricyclics as indoleamine-2, 3-dioxygenase (IDO) antagonists for the treatment of cancer | 默克专利有限公司 | 2021-08-06 | — | — | CN | disclosed |