Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.71 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13755349 | 0.84 | SLC6A4 (0.72) | SLC6A4SLC6A3SLC6A2GRIN1GRIN2A | |
| SCHEMBL3517955 | 0.83 | SLC6A3 (1.00) | SLC6A4SLC6A3SLC6A2GRIN1GRIN2A | |
| SCHEMBL3519993 | 0.80 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2GRIN1GRIN2A | |
| SCHEMBL20194921 | 0.79 | SLC6A4 (0.65) | SLC6A4SLC6A3SLC6A2GRIN1GRIN2A | |
| SCHEMBL19388511 | 0.78 | SLC6A4 (0.64) | SLC6A4SLC6A3SLC6A2GRIN1GRIN2A | |
| SCHEMBL10837873 | 0.77 | SLC6A4 (0.90) | SLC6A4SLC6A3SLC6A2GRIN1GRIN2A | |
| SCHEMBL13755350 | 0.76 | SLC6A4 (0.61) | SLC6A4SLC6A3SLC6A2GRIN1GRIN2A | |
| SCHEMBL14667625 | 0.75 | SLC6A4 (0.60) | SLC6A4SLC6A3SLC6A2GRIN1GRIN2A | |
| SCHEMBL15065608 | 0.74 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2GRIN1GRIN2A | |
| SCHEMBL10112726 | 0.74 | SLC6A4 (0.58) | SLC6A4SLC6A3SLC6A2GRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101341150-A | Nitroimidazole compounds | NOVARTIS AG (CH) | 2009-01-07 | — | — | CN | disclosed |