Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775559 | 0.91 | S1PR1 (0.41) | S1PR1S1PR3MAPTHTTPOLB | |
| SCHEMBL2771877 | 0.79 | PTGS2 (0.52) | MAPTNPC1RAB9APTGS2HTT | |
| SCHEMBL2773164 | 0.74 | PTGS2 (0.51) | MAPTRAB9APTGS2POLBCMA1 | |
| SCHEMBL2772724 | 0.74 | PTGS2 (0.41) | MAPTPTGS2POLBPTGDR2SMN1; SMN2 | |
| SCHEMBL319975 | 0.74 | S1PR1 (0.46) | S1PR1S1PR3MAPTNPC1RAB9A | |
| SCHEMBL2776075 | 0.72 | TTR (0.50) | MAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL256771 | 0.70 | NOTUM (0.50) | MAPTHTTPTGDR2LMNASMN1; SMN2 | |
| SCHEMBL30622268 | 0.70 | NOTUM (0.50) | MAPTHTTPTGDR2LMNASMN1; SMN2 | |
| SCHEMBL319590 | 0.70 | S1PR1 (0.52) | S1PR1S1PR3POLB | |
| SCHEMBL3183891 | 0.70 | CA12 (0.51) | MAPTNPC1RAB9AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193125-A2 | OXADIAZOLE DERIVATIVES | Merck Serono S.A. (CH) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009043889-A2 | OXADIAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2009-04-09 | — | — | WO | disclosed |