Broxuridine

Broxuridine

SCHEMBL27756

O=c1[nH]c(=O)n(C2CC(O)C(CO)O2)cc1Br

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TK1 P04183 3/20 0.73
LMNA P02545 2/20 0.73
SMN1; SMN2 Q16637 2/20 0.73
CYP1A2 P05177 1/20 0.69
CYP3A4 P08684 1/20 0.69
TSHR P16473 1/20 0.69
BLM P54132 1/20 0.69
PMP22 Q01453 1/20 0.69
NPSR1 Q6W5P4 1/20 0.69
ALOX12 P18054 1/20 0.69
ADRA1A P35348 1/20 0.69
TK2 O00142 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Broxuridine SCHEMBL37420 1.00 TK1 (0.73) TK1LMNASMN1; SMN2CYP1A2CYP3A4
Broxuridine SCHEMBL10316347 1.00 TK1 (0.73) TK1LMNASMN1; SMN2CYP1A2CYP3A4
Broxuridine SCHEMBL65484 1.00 TK1 (0.73) TK1LMNASMN1; SMN2CYP1A2CYP3A4
Broxuridine SCHEMBL14457631 1.00 TK1 (0.73) TK1LMNASMN1; SMN2CYP1A2CYP3A4
Broxuridine SCHEMBL9153195 1.00 TK1 (0.73) TK1LMNASMN1; SMN2CYP1A2CYP3A4
Broxuridine SCHEMBL27755 1.00 TK1 (0.73) TK1LMNASMN1; SMN2CYP1A2CYP3A4
Broxuridine SCHEMBL20769775 1.00 TK1 (0.73) TK1LMNASMN1; SMN2CYP1A2CYP3A4
Broxuridine SCHEMBL21137660 1.00 TK1 (0.73) TK1LMNASMN1; SMN2CYP1A2CYP3A4
Broxuridine SCHEMBL21423028 1.00 TK1 (0.73) TK1LMNASMN1; SMN2CYP1A2CYP3A4
Broxuridine SCHEMBL5981680 1.00 TK1 (0.73) TK1LMNASMN1; SMN2CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6610 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250275946-A1 COMBINATION THERAPY FOR THE TREATMENT OF CANCER UNM RAINFOREST INNOVATIONS (US) 2025-09-04 US claimed
EP-4056711-B1 METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES SOMALOGIC OPERATING CO INC (US) 2025-09-03 EP claimed
US-20250147022-A1 Multiplexed Analyses of Test Samples SOMALOGIC OPERATING CO., INC. (US) 2025-05-08 US claimed
CN-119948173-A Modified molecular beacons for improved detection specificity 贝克顿迪金森公司 2025-05-06 CN claimed
CN-119614490-A Myocardial cell culture method 西南医科大学附属医院 2025-03-14 CN claimed
CN-119023366-A Amniotic fluid chromosome nuclear pancreatin harvesting method for automatic cell harvester 绍兴市妇幼保健院 2024-11-26 CN claimed
CN-118638898-A Method for targeted nucleic acid sequence enrichment and use in error-correcting nucleic acid sequencing 华盛顿大学 2024-09-13 CN claimed
CN-118510907-A Use of decoy polynucleotides in single cell multinomial 贝克顿迪金森公司 2024-08-16 CN claimed
CN-118064441-A Methods of producing aptamers with improved dissociation rates 私募蛋白质体运营有限公司 2024-05-24 CN claimed
CN-116574698-A TK-deleted bovine nodular skin disease virus and application thereof 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) 2023-08-11 CN claimed
EP-0450370-A1 Branch migration of nucleotides ENZO BIOCHEM, INC. (US) 1991-10-09 EP claimed
WO-1990010277-A1 METHOD AND APPARATUS FOR DETERMINING A PROLIFERATION INDEX OF A CELL SAMPLE CELL ANALYSIS SYSTEMS, INC. (US) 1990-09-07 WO claimed
EP-0119025-B1 THYMIDINE KINASE-NEGATIVE TEMPERATURE RESISTANT BOVINE HERPESVIRUS-1 MUTANT AS A VACCINE AGAINST INFECTIOUS BOVINE RHINOTRACHEITIS Baylor College of Medicine (US) 1989-09-13 EP claimed
US-4812394-A Flow cytomeric measurement of DNA and incorporated nucleoside analogs UNIVERSITY OF CALIFORNIA (US) 1989-03-14 US claimed
US-4766067-A Gene amplification PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1988-08-23 US claimed
US-4569840-A Thymidine kinase-negative temperature resistant bovine herpesvirus-1 mutant as a vaccine against infectious bovine rhinotracheitis BAYLOR COLLEGE OF MEDICINE (US) 1986-02-11 US claimed
US-4529700-A Hybridoma cells secreting a monoclonal antibody specific for 5-bromo and 5-iodoeoxyuridine and reagents for measuring cellular proliferation UNIVERSITY OF MIAMI (US) 1985-07-16 US claimed
EP-0119025-A2 Thymidine kinase-negative temperature resistant bovine herpesvirus-1 mutant as a vaccine against infectious bovine rhinotracheitis Baylor College of Medicine (US) 1984-09-19 EP claimed
US-4465769-A Non-transformed thymidine kinaseless cell line and its use for testing tumorigenic potential of genes THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1984-08-14 US claimed
EP-0102228-A2 Hybridoma secreting a monoclonal antibody specific for 5-bromo and 5-iododeoxyuridine and reagent for measuring cellular proliferation UNIVERSITY OF MIAMI (US) 1984-03-07 EP claimed