Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 8/20 | 0.44 |
| ▸ | GRM8 | O00222 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3577615 | 0.80 | ALDH1A1 (0.65) | MAPTALDH1A1KDM4ETP53LMNA | |
| SCHEMBL3577611 | 0.80 | ALDH1A1 (0.65) | MAPTALDH1A1KDM4ETP53LMNA | |
| SCHEMBL27777349 | 0.78 | MAPT (0.48) | MAPTALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL3579808 | 0.78 | MAPT (0.50) | MAPTALDH1A1KDM4ETP53MEN1 | |
| SCHEMBL19221480 | 0.75 | GRM4 (0.68) | GRM4GRM8MAPTKDM4EGRIK1 | |
| SCHEMBL3584921 | 0.75 | MAPT (0.50) | MAPTALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL27756486 | 0.74 | AKR1C3 (0.45) | MAPTALDH1A1KDM4ETP53MEN1 | |
| SCHEMBL3574447 | 0.74 | AKR1C3 (0.58) | MAPT | |
| SCHEMBL16775013 | 0.72 | MAPT (0.60) | MAPTALDH1A1KDM4ETP53HTT | |
| SCHEMBL27827480 | 0.72 | MAPT (0.52) | MAPTALDH1A1KDM4ETP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101528670-A | 2-hydroxy-1, 3-diaminopropane derivatives | NOVARTIS AG (CH) | 2009-09-09 | — | — | CN | disclosed |