Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1640680 | 0.93 | RXFP1 (0.45) | RXFP1MEN1KMT2ATP53MAPT | |
| SCHEMBL27777483 | 0.90 | RXFP1 (0.43) | RXFP1MEN1KMT2ATP53MAPT | |
| SCHEMBL1639052 | 0.87 | RXFP1 (0.40) | RXFP1MEN1KMT2ATP53MAPT | |
| SCHEMBL3836486 | 0.86 | RXFP1 (0.42) | RXFP1MEN1KMT2ATP53MAPT | |
| SCHEMBL1639088 | 0.80 | RXFP1 (0.44) | RXFP1MEN1KMT2ATP53MAPT | |
| SCHEMBL27756391 | 0.79 | P2RY12 (0.42) | RXFP1MEN1KMT2ATP53MAPT | |
| SCHEMBL3834758 | 0.76 | RXFP1 (0.41) | RXFP1MEN1KMT2ATP53MAPT | |
| SCHEMBL1640694 | 0.75 | RAB9A (0.44) | RXFP1MEN1KMT2ATP53MAPT | |
| SCHEMBL4426718 | 0.75 | P2RY12 (0.49) | RXFP1MEN1KMT2ATP53MAPT | |
| SCHEMBL14273359 | 0.74 | RXFP1 (0.42) | RXFP1MEN1KMT2ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101534832-A | Substituted nitrogen containing heterocycles as platelet ADP receptor inhibitors | PORTOLA PHARM INC (US) | 2009-09-16 | — | — | CN | claimed |
| CN-101534832-A | Substituted nitrogen containing heterocycles as platelet ADP receptor inhibitors | PORTOLA PHARM INC (US) | 2009-09-16 | — | — | CN | disclosed |