Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 5/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3025038 | 1.00 | S1PR3 (0.44) | S1PR3IDO1RORCARALDH1A1 | |
| SCHEMBL3025433 | 0.88 | IDO1 (0.45) | S1PR3IDO1RORCARALDH1A1 | |
| SCHEMBL3033130 | 0.86 | S1PR3 (0.42) | S1PR3IDO1RORCARALDH1A1 | |
| SCHEMBL3031514 | 0.84 | RORC (0.42) | S1PR3IDO1RORCARALDH1A1 | |
| SCHEMBL3027062 | 0.84 | RORC (0.43) | S1PR3IDO1RORCARALDH1A1 | |
| SCHEMBL3029565 | 0.83 | RORC (0.42) | S1PR3IDO1RORCARALDH1A1 | |
| Hydrochloric Acid SCHEMBL3025489 | 0.83 | RORC (0.42) | S1PR3IDO1RORCARALDH1A1 | |
| SCHEMBL3025151 | 0.82 | RORC (0.41) | S1PR3IDO1RORCARALDH1A1 | |
| SCHEMBL28779023 | 0.82 | AR (0.43) | IDO1RORCARALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL3024257 | 0.82 | RORC (0.41) | S1PR3IDO1RORCARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101522190-A | Pyrrolidinone anilines as progesterone receptor modulators | SMITHKLINE BEECHAM CORP (US) | 2009-09-02 | — | — | CN | disclosed |