Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775946 | 0.90 | PPARA (0.45) | PPARAATMKMT2ACCR1DYRK1A | |
| SCHEMBL2774687 | 0.86 | CCR1 (0.45) | PPARAATMKMT2ACCR1DYRK1A | |
| Hydrochloric Acid SCHEMBL2775097 | 0.85 | PPARA (0.50) | PPARADYRK1ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2774177 | 0.84 | PPARA (0.55) | PPARAATMKMT2ADYRK1ANPC1 | |
| SCHEMBL6518766 | 0.81 | PPARA (0.47) | PPARAATMDYRK1ANPC1RAB9A | |
| SCHEMBL2773958 | 0.79 | DYRK1A (0.58) | PPARAKMT2ADYRK1ANPC1RAB9A | |
| SCHEMBL12789618 | 0.76 | CCR1 (0.47) | KMT2ACCR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2776775 | 0.71 | SMN1; SMN2 (0.52) | ATMKMT2ACCR1RAB9ASMN1; SMN2 | |
| SCHEMBL4768526 | 0.69 | PPARA (0.51) | PPARASMN1; SMN2ALDH1A1 | |
| SCHEMBL2773596 | 0.69 | CCR1 (0.55) | KMT2ACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |