Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 13/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2777758 | 0.80 | CCR1 (0.59) | CCR1KMT2ALMNATSHR | |
| SCHEMBL2777378 | 0.80 | CCR1 (0.52) | CCR1KMT2ALMNATSHRKCNH2 | |
| SCHEMBL2775803 | 0.79 | CCR1 (0.55) | CCR1KMT2ALMNATSHRKCNH2 | |
| SCHEMBL2780495 | 0.79 | CCR1 (0.55) | CCR1KMT2ALMNATSHRKCNH2 | |
| SCHEMBL2774188 | 0.78 | CCR1 (0.57) | CCR1KMT2ALMNATSHRKCNH2 | |
| SCHEMBL2775294 | 0.77 | CCR1 (0.53) | CCR1KMT2ALMNATSHRKCNH2 | |
| SCHEMBL4097076 | 0.77 | CCR5 (0.42) | KMT2A | |
| SCHEMBL6521562 | 0.76 | DPP4 (0.38) | CCR1KMT2AKCNH2 | |
| SCHEMBL2777112 | 0.76 | CCR1 (0.52) | CCR1KMT2ALMNATSHRKCNH2 | |
| SCHEMBL2774895 | 0.74 | KMT2A (0.53) | CCR1KMT2ALMNATSHRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |