Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 4/20 | 0.42 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14392659 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14368689 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14368693 | 0.85 | KMT2A (0.55) | ALDH1A1HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14392349 | 0.85 | KMT2A (0.55) | ALDH1A1HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27778266 | 0.85 | HRH3 (0.48) | ALDH1A1 | |
| SCHEMBL14368747 | 0.85 | HRH3 (0.48) | ALDH1A1 | |
| SCHEMBL27757345 | 0.84 | SSTR3 (0.55) | NPC1RAB9ACCR3SSTR3 | |
| SCHEMBL14368669 | 0.84 | SSTR3 (0.55) | NPC1RAB9ACCR3SSTR3 | |
| SCHEMBL4423112 | 0.82 | KDM4E (0.47) | ALDH1A1KMT2ANPC1RAB9ATSHR | |
| SCHEMBL14368810 | 0.82 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | claimed |
| CN-101484442-A | Compounds that are agonists of muscarinic receptors and tha may be effective in treating pain, alzheimer's disease and/or schizophrenia | ASTRAZENECA AB (SE) | 2009-07-15 | — | — | CN | disclosed |