Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 18/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27757617 | 0.70 | ALDH1A1 (0.46) | PDE4BPDE4D | |
| SCHEMBL25003079 | 0.68 | MEN1 (0.66) | PDE4BPDE4D | |
| SCHEMBL27757627 | 0.68 | TRPV1 (0.61) | GPR52 | |
| SCHEMBL13121716 | 0.66 | GPR52 (0.60) | GPR52 | |
| SCHEMBL2853640 | 0.64 | GPR52 (0.70) | GPR52 | |
| SCHEMBL2853636 | 0.64 | GPR52 (0.70) | GPR52 | |
| SCHEMBL2856224 | 0.64 | GPR52 (0.70) | GPR52 | |
| SCHEMBL6971328 | 0.63 | GPR52 (0.68) | GPR52 | |
| SCHEMBL9671269 | 0.61 | GPR52 (0.66) | GPR52 | |
| SCHEMBL9352721 | 0.61 | GPR52 (0.66) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101423502-A | 1-heterocycle-5-phenyl-2amylene-1-ones compounds as well as preparation method and application thereof | UNIV CHINA AGRICULTURAL (CN) | 2009-05-06 | — | — | CN | disclosed |