Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2449592 | 0.95 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL759392 | 0.75 | — | — | |
| SCHEMBL8757241 | 0.74 | — | — | |
| SCHEMBL3462114 | 0.74 | — | — | |
| SCHEMBL11659916 | 0.73 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL18184332 | 0.72 | — | — | |
| SCHEMBL4195938 | 0.71 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL25045881 | 0.69 | ACACB (0.36) | ALDH1A1 | |
| SCHEMBL1730499 | 0.69 | CYP2C9 (0.31) | — | |
| SCHEMBL23978886 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100378105-C | Pyran isoflavone molluscacide synthesizing method and formulation | NANJING MILITARY AREA COMBINED (CN) | 2008-04-02 | — | — | CN | claimed |
| CN-1521164-A | Pyran isoflavone molluscacide synthesizing method and formulation | 中国人民解放军南京军区联勤部军事医 | 2004-08-18 | — | — | CN | claimed |
| CN-1431209-A | Method for synthesizing molluscacide (Al pinumisoflavone) of pyrane isoflavone and its product | INST OF MILITARY MEDICINE IN D (CN) | 2003-07-23 | — | — | CN | claimed |
| EP-0775130-B1 | METHOD FOR THE PREPARATION OF (+/-)-CALANOLIDE A AND INTERMEDIATES THEREOF | SARAWAK MEDICHEM PHARMACEUTICALS INC (US) | 2003-05-02 | — | — | EP | claimed |
| JP-3043813-B2 | — | — | 2000-05-22 | — | — | JP | claimed |
| WO-1998038193-A1 | METHOD FOR THE PREPARATION OF (+)-CALANOLIDE A AND ANALOGUES THEREOF | MEDICHEM RESEARCH, INC. (US) | 1998-09-03 | — | — | WO | claimed |
| EP-0775130-A1 | METHOD FOR THE PREPARATION OF (+/-)-CALANOLIDE A AND INTERMEDIATES THEREOF | MEDICHEM RESEARCH, INC. (US) | 1997-05-28 | — | — | EP | claimed |
| WO-1996004263-A1 | METHOD FOR THE PREPARATION OF (±)-CALANOLIDE A AND INTERMEDIATES THEREOF | MEDICHEM RESEARCH, INC. (US) | 1996-02-15 | — | — | WO | claimed |
| US-5489697-A | Method for the preparation of (+)-calanolide A and intermediates thereof | MEDICHEM RESEARCH, INC. (US) | 1996-02-06 | — | — | US | claimed |
| CN-116239473-A | Alcohol-based polyether compound with symmetrical structure, and preparation method and application thereof | 新凤鸣集团股份有限公司 | 2023-06-09 | — | — | CN | disclosed |
| EP-2231143-B1 | 5H-pyrido[4,3-b]indoles as INHIBITORS OF JANUS KINASES | MERCK SHARP & DOHME (US) | 2013-07-03 | — | — | EP | disclosed |
| US-8431569-B2 | Inhibitors of janus kinases | MERCK SHARP & DOHME CORP. (US) | 2013-04-30 | — | — | US | disclosed |
| US-20100267709-A1 | INHIBITORS OF JANUS KINASES | MERCK SHARP & DOHME LLC | 2010-10-21 | — | — | US | disclosed |
| EP-2231143-A1 | INHIBITORS OF JANUS KINASES | Merck Sharp & Dohme Corp. (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-1998038193-A1 | METHOD FOR THE PREPARATION OF (+)-CALANOLIDE A AND ANALOGUES THEREOF | MEDICHEM RESEARCH, INC. (US) | 1998-09-03 | — | — | WO | disclosed |
| EP-0775130-A1 | METHOD FOR THE PREPARATION OF (+/-)-CALANOLIDE A AND INTERMEDIATES THEREOF | MEDICHEM RESEARCH, INC. (US) | 1997-05-28 | — | — | EP | disclosed |
| US-5576426-A | Aldolase catalyzed stereoselective synthesis of arabinohexulose, xyloheptulose, threohexulose and xylohexulose | G. D. SEARLE & CO. (US) | 1996-11-19 | — | — | US | disclosed |
| WO-1996004263-A1 | METHOD FOR THE PREPARATION OF (±)-CALANOLIDE A AND INTERMEDIATES THEREOF | MEDICHEM RESEARCH, INC. (US) | 1996-02-15 | — | — | WO | disclosed |
| US-5489697-A | Method for the preparation of (+)-calanolide A and intermediates thereof | MEDICHEM RESEARCH, INC. (US) | 1996-02-06 | — | — | US | disclosed |
| US-5143831-A | Fructose 1,6-diphosphate aldolase catalyzed steroselective synthesis of sugars | G. D. SEARLE & CO. (US) | 1992-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267709-A1 | INHIBITORS OF JANUS KINASES | JAK2, JAK3, JAK1 | ALDH1A1 3244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.