Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623887 | 0.79 | DAO (0.50) | DAOKDM4EHSD17B10HPGDSRD5A2 | |
| SCHEMBL27780125 | 0.77 | DAO (0.45) | DAOKDM4EHSD17B10HPGDSRD5A2 | |
| SCHEMBL69502 | 0.73 | DAO (0.51) | DAOKDM4EHSD17B10HPGDSRD5A2 | |
| SCHEMBL27779792 | 0.70 | DAO (0.49) | DAOKDM4EHSD17B10HPGDSRD5A2 | |
| SCHEMBL4393058 | 0.70 | DAO (0.47) | DAOKDM4EHSD17B10HPGDSRD5A2 | |
| SCHEMBL1244830 | 0.69 | DAO (0.48) | DAOKDM4EHSD17B10HPGDSRD5A2 | |
| SCHEMBL1244120 | 0.68 | HRH4 (0.56) | DAOKDM4EHSD17B10HPGDSRD5A2 | |
| SCHEMBL1243913 | 0.68 | DAO (0.53) | DAOKDM4EHSD17B10HPGDSRD5A2 | |
| SCHEMBL1244150 | 0.68 | DAO (0.53) | DAOKDM4EHSD17B10HPGDSRD5A2 | |
| SCHEMBL1244709 | 0.68 | DAO (0.53) | DAOKDM4EHSD17B10HPGDSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101511832-A | Fused heterocyclic inhibitors of D-amino acid oxidase | SEPRACOR INC (US) | 2009-08-19 | — | — | CN | disclosed |