Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | HNF4A | P41235 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | DPYD | Q12882 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1244698 | 0.75 | DAO (0.53) | DAOHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL1244700 | 0.75 | DAO (0.53) | DAOHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL28441694 | 0.74 | DAO (0.54) | DAOHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL1242725 | 0.71 | DAO (0.61) | DAOHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL27758548 | 0.70 | GPR35 (0.45) | DAOALDH1A1MEN1KMT2APTGS1 | |
| SCHEMBL27758741 | 0.70 | DAO (0.46) | DAOHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL1243834 | 0.69 | DAO (0.56) | DAOHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL1243981 | 0.69 | DAO (0.59) | DAOHPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL1243935 | 0.69 | DAO (0.59) | DAOHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL1242680 | 0.69 | DAO (0.59) | DAOHPGDHSD17B10ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101511832-A | Fused heterocyclic inhibitors of D-amino acid oxidase | SEPRACOR INC (US) | 2009-08-19 | — | — | CN | disclosed |