Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrole SCHEMBL16763188 | 0.91 | DAO (0.45) | DAOKDM4EHPGDHSD17B10GPR35 | |
| SCHEMBL22688131 | 0.80 | CYP1A2 (0.44) | DAOKDM4EHPGDHSD17B10MAPT | |
| SCHEMBL1243913 | 0.78 | DAO (0.53) | DAOKDM4EHPGDHSD17B10GPR35 | |
| SCHEMBL1244120 | 0.78 | HRH4 (0.56) | DAOKDM4EHPGDHSD17B10GPR35 | |
| SCHEMBL1244709 | 0.78 | DAO (0.53) | DAOKDM4EHPGDHSD17B10GPR35 | |
| SCHEMBL31229651 | 0.77 | KDM4E (0.42) | KDM4EHPGDHSD17B10ALDH1A1GAA | |
| SCHEMBL1244590 | 0.77 | RAB9A (0.51) | KDM4EHPGDHSD17B10MAPTALOX15 | |
| SCHEMBL6623887 | 0.75 | DAO (0.50) | DAOKDM4EHPGDHSD17B10GPR35 | |
| SCHEMBL23293694 | 0.74 | DAO (0.49) | DAOKDM4EHPGDHSD17B10GPR35 | |
| SCHEMBL6053037 | 0.74 | DAO (0.49) | DAOKDM4EHPGDHSD17B10GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1088824-B1 | Bicyclic pyrrolyl amides as glycogen phosphorylase inhibitors | PFIZER PROD INC (US) | 2004-01-07 | — | — | EP | claimed |
| US-20030195361-A1 | Bicyclic pyrrolyl amides as glycogen phosphorylase inhibitors | PFIZER INC. | 2003-10-16 | — | — | US | claimed |
| US-20020183369-A1 | Bicyclic pyrrolyl amides as glycogen phosphorylase inhibitors | DU BOIS DAISY JOE (US) | 2002-12-05 | — | — | US | claimed |
| US-6399601-B1 | ANTIDIABETIC AGENTS; NERVOUS SYSTEM DISORDERS; ANTICHOLESTEROL AGENTS | PFIZER INC. | 2002-06-04 | — | — | US | claimed |
| EP-1088824-A2 | Bicyclic pyrrolyl amides as glycogen phosphorylase inhibitors | Pfizer Products Inc. (US) | 2001-04-04 | — | — | EP | claimed |
| US-20260098047-A1 | Anti-Giardial Compounds | COMMW SCIENT IND RES ORG (AU) | 2026-04-09 | — | — | US | disclosed |
| US-20250051638-A1 | POWDERED FLUOROCHROME COMPOSITION, RESIN COMPOSITION, MOLDED ARTICLE, AND METHOD FOR PRODUCING POWDERED FLUOROCHROME COMPOSITION | DIC CORPORATION (JP) | 2025-02-13 | — | — | US | disclosed |
| CN-118434822-A | Powdery pigment composition, method for producing powdery pigment composition, resin composition, and molded article | DIC株式会社 | 2024-08-02 | — | — | CN | disclosed |
| WO-2024011294-A1 | ANTI-GIARDIAL COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2024-01-18 | — | — | WO | disclosed |
| EP-3059288-B1 | RESIN COMPOSITION AND MOLDED ARTICLE | DAINIPPON INK & CHEMICALS (JP) | 2021-12-22 | — | — | EP | disclosed |
| US-20210030895-A1 | RESIN COMPOSITION AND MOLDED ARTICLE | DIC CORPORATION (JP) | 2021-02-04 | — | — | US | disclosed |
| US-20210024821-A1 | RESIN COMPOSITION AND MOLDED ARTICLE | DIC CORPORATION (JP) | 2021-01-28 | — | — | US | disclosed |
| US-20020006946-A1 | Tetrazole compounds as thyroid receptor ligands | PFIZER INC. | 2002-01-17 | — | — | US | disclosed |
| US-20010046958-A1 | Methods of treating diabetic cardiomyopathy using glycogen phosphorylase inhibitors | TREADWAY JUDITH L (US) | 2001-11-29 | — | — | US | disclosed |
| US-20010046956-A1 | Methods of treating obesity using a neurotensin receptor ligand | HADCOCK JOHN R (US) | 2001-11-29 | — | — | US | disclosed |
| EP-1157695-A1 | Method of treating obesity using a neurotensin receptor ligand | Pfizer Products Inc. (US) | 2001-11-28 | — | — | EP | disclosed |
| EP-1136071-A2 | Use of glycogen phosphorylase inhibitors | Pfizer Products Inc. (US) | 2001-09-26 | — | — | EP | disclosed |
| EP-1127882-A1 | Tetrazole compounds as thyroid receptor ligands | Pfizer Products Inc. (US) | 2001-08-29 | — | — | EP | disclosed |
| EP-1125580-A2 | Methods of treating diabetic cardiomyopathy using glycogen phosphorylase inhibitors | Pfizer Products Inc. (US) | 2001-08-22 | — | — | EP | disclosed |
| EP-1088824-A2 | Bicyclic pyrrolyl amides as glycogen phosphorylase inhibitors | Pfizer Products Inc. (US) | 2001-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030195361-A1 | Bicyclic pyrrolyl amides as glycogen phosphorylase inhibitors | PYGL, GYS1, PYGM | DAO 1915/4885KDM4E 3388/4885HPGD 797/4885 |
| US-20010046958-A1 | Methods of treating diabetic cardiomyopathy using glycogen phosphorylase inhibitors | PYGM, GYS1, PYGL | DAO 1094/4885KDM4E 1287/4885HPGD 2615/4885 |
| US-20260098047-A1 | Anti-Giardial Compounds | GNAO1, GPR6, MGAT3 | DAO 1040/4885KDM4E 3910/4885HPGD 2504/4885 |
| US-20210030895-A1 | RESIN COMPOSITION AND MOLDED ARTICLE | IK, CBR3, RER1 | DAO 1439/4885KDM4E 1200/4885HPGD 1508/4885 |
| US-20020006946-A1 | Tetrazole compounds as thyroid receptor ligands | TSHR, THRA, THRB | DAO 1344/4885KDM4E 3587/4885HPGD 1957/4885 |
| US-20020183369-A1 | Bicyclic pyrrolyl amides as glycogen phosphorylase inhibitors | PYGL, PYGM, PYGB | DAO 1906/4885KDM4E 2517/4885HPGD 697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.