Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3990255 | 0.92 | KDM4E (0.47) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL15701587 | 0.92 | NOTUM (0.48) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL1367340 | 0.90 | GABRA1 (0.43) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL1606267 | 0.90 | TSHR (0.42) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL828480 | 0.85 | GABRA1 (0.48) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL13948752 | 0.85 | GABRA1 (0.48) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL3990274 | 0.84 | MAPT (0.47) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL17184949 | 0.82 | CA12 (0.47) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL15105925 | 0.82 | EGFR (0.48) | GABRA1GABRG2GABRB3GABRA3CA12 | |
| SCHEMBL16502360 | 0.81 | GABRA1 (0.40) | GABRA1GABRG2GABRB3GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134005-B2 | Preparation and use of magnesium amides | Ludwig-Maximilians-Universitat München (DE) | 2012-03-13 | — | — | US | disclosed |
| US-20100144516-A1 | PREPARATION AND USE OF MAGNESIUM AMIDES | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2010-06-10 | — | — | US | disclosed |
| US-20090176988-A1 | Preparation and Use of Magnesium Amides | LUDWIG-MAXIMILIANS-UNIVERSITAT MUENCHEN (DE) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176988-A1 | Preparation and Use of Magnesium Amides | MLX, GLRX3, SFXN3 | GABRA1 735/4885GABRG2 434/4885GABRB3 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.