Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 5/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716596 | 0.92 | ATM (0.55) | ATMHSP90AA1GAANPC1RAB9A | |
| SCHEMBL2329814 | 0.92 | ATM (0.55) | ATMHSP90AA1GAANPC1RAB9A | |
| Water SCHEMBL7994044 | 0.90 | ATM (0.53) | ATMHSP90AA1GAANPC1RAB9A | |
| SCHEMBL11361358 | 0.80 | SMN1; SMN2 (0.57) | GAANPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL2358014 | 0.78 | ATM (0.64) | ATMHSP90AA1GAANPC1RAB9A | |
| SCHEMBL8062605 | 0.78 | TDP1 (0.47) | ATMHSP90AA1GAANPC1RAB9A | |
| SCHEMBL6680719 | 0.77 | PGR (0.47) | ATMHSP90AA1GAANPC1RAB9A | |
| SCHEMBL11691009 | 0.76 | PARP10 (0.55) | HSP90AA1NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8311827 | 0.75 | ATM (0.56) | ATMHSP90AA1GAANPC1RAB9A | |
| SCHEMBL7754750 | 0.75 | PGR (0.48) | ATMNPC1RAB9AALDH1A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541773-A | Benzo[1,2,3]thiadiazine derivatives | EGIS GYOGYSZERGYAR NYILVANOSAN (HU) | 2009-09-23 | — | — | CN | disclosed |