SCHEMBL2358014

SCHEMBL2358014

O=C(c1ccccc1)C(Cl)C(=O)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 3/20 0.64
GAA P10253 2/20 0.64
HSP90AA1 P07900 2/20 0.64
NPC1 O15118 1/20 0.64
RAB9A P51151 1/20 0.64
ALDH1A1 P00352 4/20 0.56
GPR55 Q9Y2T6 2/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
TDP1 Q9NUW8 3/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
CES1 P23141 5/20 0.54
CES2 O00748 4/20 0.54
LMNA P02545 2/20 0.54
TSHR P16473 2/20 0.50
DAO P14920 1/20 0.50
NAPRT Q6XQN6 1/20 0.50
MDM2 Q00987 1/20 0.50
MAPK1 P28482 2/20 0.46
TRPA1 O75762 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2861674 0.90 ATM (0.60) ATMGAAHSP90AA1NPC1RAB9A
SCHEMBL8478316 0.88 ATM (0.58) ATMGAAHSP90AA1NPC1RAB9A
SCHEMBL29254343 0.86 ATM (0.56) ATMGAAHSP90AA1NPC1RAB9A
SCHEMBL8311827 0.86 ATM (0.56) ATMGAAHSP90AA1NPC1RAB9A
SCHEMBL2329814 0.85 ATM (0.55) ATMGAAHSP90AA1NPC1RAB9A
SCHEMBL10716596 0.85 ATM (0.55) ATMGAAHSP90AA1NPC1RAB9A
SCHEMBL24188 0.84 TDP1 (0.56) ATMGAAHSP90AA1NPC1RAB9A
SCHEMBL2238176 0.84 TDP1 (0.56) ATMGAAHSP90AA1NPC1RAB9A
SCHEMBL11180835 0.84 ALDH1A1 (0.57) ATMGAAHSP90AA1NPC1RAB9A
Water SCHEMBL7994044 0.83 ATM (0.53) ATMGAAHSP90AA1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120248679-B Ultraviolet absorber and preparation method thereof 襄阳金达成精细化工有限公司 2025-09-30 CN disclosed
CN-120248679-A Ultraviolet absorber and preparation method thereof 襄阳金达成精细化工有限公司 2025-07-04 CN disclosed
CN-114315865-A Flomoxef process impurity and preparation method thereof 北京济美堂医药研究有限公司 2022-04-12 CN disclosed
CN-113861006-A Chlorination method of 1, 3-dicarbonyl compound 北京工商大学 2021-12-31 CN disclosed
EP-1565518-B2 STABILIZER COMPOSITION FOR FOAMS OF HALOGEN-CONTAINING POLYMERS BAERLOCHER GMBH (DE) 2015-06-17 EP disclosed
EP-1694768-B2 STABILIZER COMPOSITION FOR HALOGENATED POLYMERS BAERLOCHER GMBH (DE) 2011-08-03 EP disclosed
EP-1912892-B1 SOLID SALT PREPARATION, THE PRODUCTION THEREOF AND ITS USE BAERLOCHER GMBH (DE) 2010-09-22 EP disclosed
EP-1565518-B1 STABILIZER COMPOSITION FOR FOAMS OF HALOGEN-CONTAINING POLYMERS BAERLOCHER GMBH (DE) 2008-07-09 EP disclosed
EP-1565517-B1 SALT OF A HALOGEN-CONTAINING OXYACID CARRIED BY A CARRIER AS A STABILISATION COMPOSITION FOR HALOGEN-CONTAINING POLYMERS BAERLOCHER GMBH (DE) 2007-04-11 EP disclosed
EP-1694768-B1 STABILIZER COMPOSITION FOR HALOGENATED POLYMERS BAERLOCHER GMBH (DE) 2007-02-14 EP disclosed
EP-1366114-B1 STABILIZER COMPOSITIONS FOR HALOGENATED POLYMERS, THE USE THEREOF AND POLYMERS CONTAINING SAID COMPOSITIONS BAERLOCHER GMBH (DE) 2006-04-19 EP disclosed
EP-1379582-B1 STABILISER COMBINATION FOR HALOGENATED POLYMERS AND THE USE THEREOF BAERLOCHER GMBH (DE) 2005-11-23 EP disclosed
US-3932338-A POLYOLEFINS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-01-13 US disclosed