Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28043228 | 0.93 | NAAA (0.32) | NAAA | |
| SCHEMBL9359034 | 0.85 | — | — | |
| SCHEMBL28430945 | 0.82 | CETP (0.33) | CETPCNR1CNR2 | |
| SCHEMBL11119933 | 0.80 | SIRT2 (0.33) | CETP | |
| SCHEMBL9800899 | 0.80 | SIRT2 (0.33) | CETP | |
| SCHEMBL9212920 | 0.79 | TSHR (0.35) | CETPCNR1CNR2 | |
| SCHEMBL9210514 | 0.79 | TSHR (0.35) | CETPCNR1CNR2 | |
| SCHEMBL9212119 | 0.79 | TSHR (0.35) | CETPCNR1CNR2 | |
| SCHEMBL9211324 | 0.79 | TSHR (0.35) | CETPCNR1CNR2 | |
| SCHEMBL9205568 | 0.79 | TSHR (0.35) | CETPCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101535260-B | Thiophene compounds | NAT HEALTH RESEARCH INSTITUTES | 2012-07-04 | — | — | CN | disclosed |
| CN-101535260-A | Thiophene compounds | NAT HEALTH RESEARCH INSTITUTES (CN) | 2009-09-16 | — | — | CN | disclosed |