Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 10/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554121 | 0.86 | ALOX5 (0.51) | ALOX5MAOBCYP3A4RAB9ANPC1 | |
| SCHEMBL30663841 | 0.86 | MAOB (0.56) | ALOX5MAOBRAB9ANPC1MAOA | |
| SCHEMBL498282 | 0.86 | MAOB (0.56) | ALOX5MAOBRAB9ANPC1MAOA | |
| SCHEMBL8335885 | 0.81 | ALOX5 (0.61) | ALOX5MAOBRAB9ANPC1MAOA | |
| SCHEMBL4839224 | 0.80 | ALDH1A1 (0.61) | MAOBPKMMEN1KMT2A | |
| SCHEMBL4839242 | 0.80 | ALDH1A1 (0.61) | MAOBPKMMEN1KMT2A | |
| SCHEMBL27685290 | 0.79 | MAOB (0.59) | ALOX5MAOBMAOALMNACYP1A2 | |
| SCHEMBL19519274 | 0.79 | MAOB (0.46) | ALOX5MAOBRAB9ANPC1MAOA | |
| SCHEMBL1439758 | 0.78 | PPARD (0.58) | ALOX5MAOBRAB9ANPC1MAOA | |
| SCHEMBL9306893 | 0.77 | MRGPRX4 (0.68) | ALOX5MAOBRAB9ANPC1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101448791-B | Fxr agonists | LILLY CO ELI | 2011-11-16 | — | — | CN | disclosed |
| CN-101448791-A | FXR agonists | LILLY CO ELI (US) | 2009-06-03 | — | — | CN | disclosed |