Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethoxycarbonyl Group SCHEMBL27796958 | 0.88 | MAPT (0.34) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Ethoxycarbonyl Group SCHEMBL27787942 | 0.86 | HRH4 (0.40) | TSHRALDH1A1MAPTL3MBTL1TDP1 | |
| Ethoxycarbonyl Group SCHEMBL27784611 | 0.86 | ERN1 (0.35) | GPR35ALDH1A1MAPTL3MBTL1TDP1 | |
| Ethoxycarbonyl Group SCHEMBL27762805 | 0.86 | HSP90AA1 (0.36) | KDM4EALDH1A1MAPTL3MBTL1TDP1 | |
| SCHEMBL2768545 | 0.85 | GRIN2D (0.49) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Ethoxycarbonyl Group SCHEMBL27818141 | 0.82 | MAPT (0.43) | ALDH1A1MAPTCYP1A2L3MBTL1CYP2C9 | |
| Ethoxycarbonyl Group SCHEMBL27809829 | 0.82 | FBP1 (0.33) | ALDH1A1MAPTHPGD | |
| Ethoxycarbonyl Group SCHEMBL27476172 | 0.82 | MAPT (0.40) | CYP3A4TSHRKDM4EALDH1A1MAPT | |
| Ethoxycarbonyl Group SCHEMBL27762839 | 0.82 | TXNRD1 (0.35) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| Ethoxycarbonyl Group SCHEMBL27784595 | 0.81 | MAPT (0.36) | ALDH1A1MAPTCYP2C19HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801965-B | Indole compounds as inhibitors of cellular necrosis | LG LIFE SCIENCES LTD | 2014-07-30 | — | — | CN | disclosed |
| CN-101896483-B | Glucokinase activators and pharmaceutical compositions containing the same as active ingredients | LG LIFE SCIENCES LTD | 2013-11-20 | — | — | CN | disclosed |
| CN-101573357-B | Indole compound | TAKAEDA CHEMICAL IND LTD | 2013-01-23 | — | — | CN | disclosed |
| CN-101896483-A | Glucokinase activators and pharmaceutical compositions containing the same as active ingredients | LG LIFE SCIENCES LTD | 2010-11-24 | — | — | CN | disclosed |
| CN-101801965-A | Indole compounds as inhibitors of cellular necrosis | LG LIFE SCIENCES LTD | 2010-08-11 | — | — | CN | disclosed |
| CN-101573357-A | Indole compound | TAKEDA PHARMACEUTICAL (JP) | 2009-11-04 | — | — | CN | disclosed |