Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4126232 | 0.83 | CA1 (0.39) | ALDH1A1TDP1KMT2ACA1CA2 | |
| SCHEMBL21216561 | 0.81 | CA1 (0.38) | ALDH1A1TDP1KMT2ACA1CA2 | |
| SCHEMBL10622854 | 0.79 | CA1 (0.45) | ALDH1A1KMT2ACA1CA2CA5A | |
| SCHEMBL6673226 | 0.79 | ALDH1A1 (0.36) | ALDH1A1KMT2ACA1CA2CA5A | |
| SCHEMBL2127256 | 0.79 | SRC (0.48) | ALDH1A1TDP1KMT2ACA1CA2 | |
| SCHEMBL16692471 | 0.79 | KMT2A (0.40) | ALDH1A1KMT2ACA1CA2CA5A | |
| SCHEMBL1572640 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TDP1KMT2AMAPT | |
| SCHEMBL27744643 | 0.73 | ALDH1A1 (0.37) | ALDH1A1HSD17B10TDP1KMT2ACA1 | |
| SCHEMBL3633092 | 0.71 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TDP1MAPK1TSHR | |
| SCHEMBL4139846 | 0.71 | POLB (0.38) | ALDH1A1KMT2ACA1CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101628888-B | Inhibitors of cytosolic phospholipase a2 | WYETH CORP | 2012-05-23 | — | — | CN | disclosed |
| CN-100503566-C | Cytosolic phospholipase A2 inhibitors | WYETH CORP (US) | 2009-06-24 | — | — | CN | disclosed |