Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4130950 | 0.80 | SRC (0.41) | ALDH1A1TSHRSRCCYP2C19CYP2D6 | |
| SCHEMBL27640855 | 0.78 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TDP1TSHRSRC | |
| SCHEMBL438263 | 0.78 | SRC (0.40) | ALDH1A1TSHRSRCCYP2C19CYP2D6 | |
| SCHEMBL669211 | 0.76 | SRC (0.54) | ALDH1A1TDP1TSHRSRCCYP2C19 | |
| SCHEMBL9006009 | 0.76 | CA1 (0.42) | ALDH1A1SRCDPP4F2 | |
| SCHEMBL5555043 | 0.76 | SRC (0.39) | ALDH1A1TSHRSRCCYP2C19CYP2D6 | |
| SCHEMBL5555050 | 0.76 | SRC (0.39) | ALDH1A1TDP1TSHRSRCCYP2C19 | |
| SCHEMBL1412817 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HSD17B10TDP1TSHRSRC | |
| SCHEMBL5886893 | 0.75 | CYP2C19 (0.48) | ALDH1A1HSD17B10TDP1TSHRSRC | |
| SCHEMBL1095271 | 0.73 | TSHR (0.48) | ALDH1A1HSD17B10TDP1TSHRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2146962-A2 | NOVEL VANILLOID RECEPTOR LIGANDS AND THE USE THEREOF FOR THE PRODUCTION OF PHARMACEUTICALS | Grünenthal GmbH (DE) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008125337-A2 | NOVEL VANILLOID RECEPTOR LIGANDS AND THE USE THEREOF FOR THE PRODUCTION OF PHARMACEUTICALS | Grünenthal GmbH (DE) | 2008-10-23 | — | — | WO | disclosed |
| CN-1076452-A | 3,4 '-dideoxy mycaminose base tylosin cyclic lactone derivatives and manufacture method thereof | ZAIDAN HOJIN BISEIBUTSU (JP) | 1993-09-22 | — | — | CN | disclosed |