SCHEMBL27764597

SCHEMBL27764597

C=CC(=O)OCCO[Si](CCCCC)(OCC)OCC

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.56
HPGD P15428 1/20 0.56
ALDH1A1 P00352 4/20 0.43
TP53 P04637 3/20 0.43
HIF1A Q16665 3/20 0.43
CYP3A4 P08684 2/20 0.43
HSD17B10 Q99714 1/20 0.43
THRB P10828 4/20 0.41
ATM Q13315 1/20 0.39
HCAR2 Q8TDS4 3/20 0.37
THRA P10827 1/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
DGKA P23743 1/20 0.34
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27795147 0.99 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27699554 0.99 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27743782 0.99 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27680759 0.99 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28814535 0.99 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27985884 0.99 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27985544 0.99 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27985547 0.99 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL27699553 0.99 TSHR (0.54) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28018806 0.89 TSHR (0.51) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103320146-B The manufacture method of crystal aligning agent, liquid crystal orienting film, liquid crystal display device and liquid crystal display device JSR株式会社 2016-06-15 CN disclosed
CN-105567258-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display assembly CHI MEI CORP 2016-05-11 CN disclosed
CN-105567257-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element CHI MEI CORP 2016-05-11 CN disclosed
CN-105324407-A Active energy ray-curable composition KANEKA CORP 2016-02-10 CN disclosed
CN-103131431-B MATERIALS FOR DISPLAY, crystal aligning agent and liquid crystal display device JSR CO., LTD. (JP) 2015-10-07 CN disclosed
CN-102311739-B The manufacture method of liquid crystal aligning agent, liquid crystal display device and liquid crystal display device JSR CO., LTD. (JP) 2015-09-16 CN disclosed
CN-104629774-A Liquid crystal orientation agent, liquid crystal orientation film and production method thereof, and liquid crystal display element and production method thereof JSR CORP 2015-05-20 CN disclosed
CN-104232107-A Liquid crystal aligning agent, phase difference membrane and manufacturing method for phase difference membrane JSR CORP 2014-12-24 CN disclosed
CN-104140826-A Liquid crystal aligning agent, liquid crystal aligning film, retardation film and methods for producing same, and liquid crystal display element JSR CORP 2014-11-12 CN disclosed
CN-103980911-A Liquid crystal alignment agent, liquid crystal alignment film, liquid crystal display element and manufacture method thereof JSR CORP 2014-08-13 CN disclosed
CN-103834415-A Liquid crystal aligning agent, phase difference film and manufacturing method for the phase difference film JSR CORP 2014-06-04 CN disclosed
CN-103788962-A Liquid crystal aligning agent for PSA mode liquid crystal display device, liquid crystal alignment film for PSA mode liquid crystal display device, and the PSA mode liquid crystal display device and manufacturing method thereof JSR CORP 2014-05-14 CN disclosed
CN-103666486-A Liquid crystal orientation agent, liquid crystal orientation film, manufacturing method of liquid crystal orientation film, and liquid crystal display element JSR CORP 2014-03-26 CN disclosed
CN-103627406-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element JSR CORP 2014-03-12 CN disclosed
CN-103320146-A Liquid crystal aligning agent, liquid crystal aligning film, liquid crystal display element and method of making liquid crystal display element JSR CORP 2013-09-25 CN disclosed
CN-101451050-B Pressure sensitive adhesive tape NITTO DENKO CORP 2013-07-10 CN disclosed
CN-103131431-A Display material, liquid crystal alignment agent and liquid crystal display element JSR CORP 2013-06-05 CN disclosed
CN-102311739-A The method of manufacture of liquid crystal aligning agent, liquid crystal display device and liquid crystal display device JSR CORP 2012-01-11 CN disclosed
CN-101812304-A Liquid crystal aligning agent, liquid crystal display device and manufacture method thereof JSR CO LTD 2010-08-25 CN disclosed
CN-101451050-A Pressure sensitive adhesive tape NITTO DENKO CORP (JP) 2009-06-10 CN disclosed