Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 4/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27985544 | 1.00 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL27699553 | 1.00 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL27985884 | 1.00 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL27795147 | 1.00 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL27985547 | 1.00 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL27743782 | 1.00 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL27680759 | 1.00 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL27699554 | 1.00 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL27764597 | 0.99 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL10601643 | 0.88 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104140733-A | Low-temperature cureable coating composition and article having cured coating thereof | SHINETSU CHEMICAL CO | 2014-11-12 | — | — | CN | disclosed |