SCHEMBL27795147

SCHEMBL27795147

C=CC(=O)OCCO[Si](CCCCCC)(OCC)OCC

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 10/20 0.54
HPGD P15428 1/20 0.54
ALDH1A1 P00352 3/20 0.46
CYP3A4 P08684 1/20 0.46
TP53 P04637 2/20 0.42
HIF1A Q16665 2/20 0.42
HSD17B10 Q99714 1/20 0.42
THRB P10828 4/20 0.40
HCAR2 Q8TDS4 3/20 0.39
ATM Q13315 1/20 0.38
THRA P10827 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
DGKA P23743 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27985544 1.00 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL27699553 1.00 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL27985884 1.00 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL28814535 1.00 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL27985547 1.00 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL27743782 1.00 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL27680759 1.00 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL27699554 1.00 TSHR (0.54) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL27764597 0.99 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL10601643 0.88 TSHR (0.61) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106795275-B Actinic-radiation curable composition 株式会社钟化 2019-03-05 CN disclosed
CN-103320146-B The manufacture method of crystal aligning agent, liquid crystal orienting film, liquid crystal display device and liquid crystal display device JSR株式会社 2016-06-15 CN disclosed
CN-102591071-B The manufacture method of liquid crystal display cells, liquid crystal display cells and aligning agent for liquid crystal JSR CO., LTD. (JP) 2016-03-16 CN disclosed
CN-105324407-A Active energy ray-curable composition KANEKA CORP 2016-02-10 CN disclosed
CN-103131431-B MATERIALS FOR DISPLAY, crystal aligning agent and liquid crystal display device JSR CO., LTD. (JP) 2015-10-07 CN disclosed
CN-102311739-B The manufacture method of liquid crystal aligning agent, liquid crystal display device and liquid crystal display device JSR CO., LTD. (JP) 2015-09-16 CN disclosed
CN-101812304-B Liquid crystal aligning agent, liquid crystal display device and fabricating method thereof JSR CO LTD 2014-03-19 CN disclosed
CN-103320146-A Liquid crystal aligning agent, liquid crystal aligning film, liquid crystal display element and method of making liquid crystal display element JSR CORP 2013-09-25 CN disclosed
CN-103131431-A Display material, liquid crystal alignment agent and liquid crystal display element JSR CORP 2013-06-05 CN disclosed
CN-102591071-A Process for producing liquid crystal display device, the liquid crystal display device, and liquid crystal aligning agent JSR CORP 2012-07-18 CN disclosed
CN-102311739-A The method of manufacture of liquid crystal aligning agent, liquid crystal display device and liquid crystal display device JSR CORP 2012-01-11 CN disclosed
CN-101812304-A Liquid crystal aligning agent, liquid crystal display device and manufacture method thereof JSR CO LTD 2010-08-25 CN disclosed