Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 2/20 | 0.47 | |
| ▸ | KDM1A | O60341 | 7/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | THPO | P40225 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17226390 | 0.89 | PDF (0.45) | PDFKDM1APIM1CHRM2HTR1A | |
| SCHEMBL22292242 | 0.86 | MAPT (0.45) | KDM1ATP53CYP1A2CYP2D6TSHR | |
| SCHEMBL31174404 | 0.82 | PDF (0.53) | PDFKDM1APIM1CHRM2HTR1A | |
| SCHEMBL28910976 | 0.82 | PDF (0.50) | PDFKDM1APIM1CHRM2HTR1A | |
| SCHEMBL28910941 | 0.82 | PDF (0.50) | PDFKDM1APIM1CHRM2HTR1A | |
| SCHEMBL28910953 | 0.82 | PDF (0.50) | PDFKDM1APIM1CHRM2HTR1A | |
| SCHEMBL28910950 | 0.82 | PDF (0.50) | PDFKDM1APIM1CHRM2HTR1A | |
| SCHEMBL27788286 | 0.80 | PDF (0.47) | PDFKDM1APIM1CHRM2HTR1A | |
| SCHEMBL30445358 | 0.79 | PDF (0.54) | PDFKDM1APIM1CHRM2HTR1A | |
| SCHEMBL16488357 | 0.79 | PDF (0.43) | PDFKDM1ATP53CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101602746-B | Preparation and application of 3-substituted-N-hexyl phenothiazine derivative | UNIV HUAZHONG NORMAL | 2012-10-10 | — | — | CN | claimed |
| CN-101602746-A | The preparation and the application thereof of 3-replacement-N-hexyl phenothiazine derivative | UNIV HUAZHONG NORMAL (CN) | 2009-12-16 | — | — | CN | claimed |
| CN-101602746-B | Preparation and application of 3-substituted-N-hexyl phenothiazine derivative | UNIV HUAZHONG NORMAL | 2012-10-10 | — | — | CN | disclosed |
| CN-101602746-A | The preparation and the application thereof of 3-replacement-N-hexyl phenothiazine derivative | UNIV HUAZHONG NORMAL (CN) | 2009-12-16 | — | — | CN | disclosed |