Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 3/20 | 0.47 | |
| ▸ | KDM1A | O60341 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28362143 | 0.82 | PDF (0.53) | PDFKDM1AMAPTSMN1; SMN2PIM1 | |
| SCHEMBL27765010 | 0.80 | PDF (0.47) | PDFKDM1AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL2784918 | 0.75 | PIM1 (0.67) | PDFKDM1AMAPTSMN1; SMN2PIM1 | |
| SCHEMBL29557345 | 0.75 | PIM1 (0.67) | PDFKDM1AMAPTSMN1; SMN2PIM1 | |
| SCHEMBL4192605 | 0.75 | PIM1 (0.67) | PDFKDM1AMAPTSMN1; SMN2PIM1 | |
| SCHEMBL7397164 | 0.75 | PIM1 (0.67) | PDFKDM1AMAPTSMN1; SMN2PIM1 | |
| SCHEMBL342329 | 0.75 | PIM1 (0.67) | PDFKDM1AMAPTSMN1; SMN2PIM1 | |
| SCHEMBL28347553 | 0.75 | PIM1 (0.67) | PDFKDM1AMAPTSMN1; SMN2PIM1 | |
| SCHEMBL31302971 | 0.75 | PIM1 (0.67) | PDFKDM1AMAPTSMN1; SMN2PIM1 | |
| SCHEMBL6120214 | 0.75 | PIM1 (0.67) | PDFKDM1AMAPTSMN1; SMN2PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101602747-A | 3, the preparation and the application thereof of 7-two replacement-N-hexyl phenothiazine derivatives | UNIV HUAZHONG NORMAL (CN) | 2009-12-16 | — | — | CN | claimed |
| CN-101602747-B | Preparation and application of 3, 7-disubstituted-N-hexyl phenothiazine derivative | UNIV HUAZHONG NORMAL | 2011-05-11 | — | — | CN | disclosed |
| CN-101602747-A | 3, the preparation and the application thereof of 7-two replacement-N-hexyl phenothiazine derivatives | UNIV HUAZHONG NORMAL (CN) | 2009-12-16 | — | — | CN | disclosed |