Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27765295 | 0.90 | ALDH1A1 (0.46) | HPGDGFERLMNASMN1; SMN2HSD17B10 | |
| SCHEMBL27765160 | 0.83 | HPGD (0.60) | HPGDGFERLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL27787214 | 0.79 | MAOB (0.62) | HPGDALDH1A1MAPT | |
| SCHEMBL27765156 | 0.79 | ALDH1A1 (0.52) | HPGDGFERLMNASMN1; SMN2HSD17B10 | |
| SCHEMBL28784418 | 0.78 | HPGD (0.62) | HPGDGFERLMNAKMT2AALDH1A1 | |
| SCHEMBL27787215 | 0.77 | ALDH1A1 (0.57) | HPGDGFERLMNASMN1; SMN2MEN1 | |
| SCHEMBL27765509 | 0.77 | POLB (0.66) | HPGDSMN1; SMN2HSD17B10KMT2AALDH1A1 | |
| SCHEMBL27765150 | 0.77 | KMT2A (0.50) | HPGDGFERLMNASMN1; SMN2HSD17B10 | |
| SCHEMBL27765512 | 0.76 | DAO (0.55) | HPGDGFERLMNAMEN1KMT2A | |
| SCHEMBL27787221 | 0.76 | CTSB (0.62) | HPGDGFERLMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101597263-A | Preparation of novel S-DABO HIV-1 reverse transcriptase inhibitor and uses thereof | UNIV CAPITAL MEDICAL (CN) | 2009-12-09 | — | — | CN | disclosed |