Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GRK2 | P25098 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL29027460 | 0.92 | HAO1 (0.36) | HAO1KMT2AMEN1LMNAPOLB | |
| Sulfuric Acid SCHEMBL27967543 | 0.90 | HAO1 (0.38) | HAO1KMT2AMEN1LMNAPOLB | |
| Sulfuric Acid SCHEMBL28087007 | 0.87 | CES2 (0.40) | HAO1KMT2AMEN1LMNAPOLB | |
| Sulfuric Acid SCHEMBL29027462 | 0.83 | CES2 (0.41) | HAO1KMT2AMEN1LMNAPOLB | |
| SCHEMBL28261269 | 0.82 | CES2 (0.40) | HAO1KMT2AMEN1LMNAPOLB | |
| SCHEMBL28573713 | 0.82 | CES2 (0.40) | HAO1KMT2AMEN1LMNAPOLB | |
| SCHEMBL28962441 | 0.82 | CES2 (0.40) | HAO1KMT2AMEN1LMNAPOLB | |
| SCHEMBL28965283 | 0.82 | CES2 (0.40) | HAO1KMT2AMEN1LMNAPOLB | |
| SCHEMBL31472461 | 0.75 | KMT2A (0.44) | HAO1KMT2AMEN1CES2CES1 | |
| SCHEMBL29109627 | 0.75 | DNM1 (0.50) | HAO1KMT2AMEN1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101597338-B | Mannan-containing ligand and preparation method and application thereof | UNIV SHANDONG | 2011-04-27 | — | — | CN | claimed |
| CN-101597338-A | A kind of part that contains mannosans and its production and application | UNIV SHANDONG (CN) | 2009-12-09 | — | — | CN | claimed |
| CN-101597338-B | Mannan-containing ligand and preparation method and application thereof | UNIV SHANDONG | 2011-04-27 | — | — | CN | disclosed |
| CN-101597338-A | A kind of part that contains mannosans and its production and application | UNIV SHANDONG (CN) | 2009-12-09 | — | — | CN | disclosed |