Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31053242 | 0.87 | GLS (0.48) | GLSKMT2AHPGDTSHRALDH1A1 | |
| SCHEMBL16673029 | 0.87 | KMT2A (0.53) | GLSKMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL5831517 | 0.86 | GLS (0.52) | GLSKMT2AHPGDTSHRALDH1A1 | |
| SCHEMBL27634779 | 0.85 | KMT2A (0.55) | GLSKMT2AHPGDTSHRALDH1A1 | |
| SCHEMBL6697396 | 0.84 | KMT2A (0.50) | GLSKMT2AHPGDALDH1A1MEN1 | |
| SCHEMBL6624926 | 0.83 | GLS (0.50) | GLSKMT2AHPGDTSHRALDH1A1 | |
| SCHEMBL16672466 | 0.83 | KMT2A (0.56) | KMT2ATSHRALDH1A1PTGS1PTGS2 | |
| SCHEMBL6899936 | 0.82 | GLS (0.49) | GLSKMT2AHPGDTSHRALDH1A1 | |
| SCHEMBL29291224 | 0.81 | NPC1 (0.54) | KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL9798388 | 0.81 | MAPT (0.51) | KMT2AHPGDALDH1A1MEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101466678-B | Substituted 3-cyanopyridines as protein kinase inhibitors | WYETH CORP | 2012-12-26 | — | — | CN | disclosed |
| CN-101466678-A | Substituted 3-cyanopyridines as protein kinase inhibitors | WYETH CORP (US) | 2009-06-24 | — | — | CN | disclosed |