Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GLS | O94925 | 8/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29291224 | 0.85 | NPC1 (0.54) | KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9798388 | 0.85 | MAPT (0.51) | KMT2AHDAC7ALDH1A1GAAL3MBTL1 | |
| SCHEMBL16673029 | 0.84 | KMT2A (0.53) | KMT2AGLSALDH1A1GAAMEN1 | |
| SCHEMBL27765337 | 0.84 | GLS (0.53) | KMT2AGLSALDH1A1GAAMEN1 | |
| SCHEMBL2250484 | 0.81 | KMT2A (0.46) | KMT2AGLSMEN1LMNAHPGD | |
| SCHEMBL16672466 | 0.80 | KMT2A (0.56) | KMT2AALDH1A1GAAMEN1SMN1; SMN2 | |
| SCHEMBL27273849 | 0.79 | ALDH1A1 (0.56) | KMT2AKDM4EALDH1A1GAAMEN1 | |
| SCHEMBL28065294 | 0.79 | KMT2A (0.55) | KMT2AALDH1A1GAAMEN1SMN1; SMN2 | |
| SCHEMBL27634779 | 0.79 | KMT2A (0.55) | KMT2AGLSALDH1A1GAAL3MBTL1 | |
| SCHEMBL9675264 | 0.79 | KMT2A (0.55) | KMT2AALDH1A1L3MBTL1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004096811-A1 | PDE9 INHIBITORS FOR TREATING TYPE 2 DIABETES, METABOKIC SYNDROME, AND CARDIOVASCULAR DISEASE | PFIZER PRODUCTS INC. (US) | 2004-11-11 | — | — | WO | disclosed |