Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.44 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.39 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | ASPH | Q12797 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31386913 | 0.74 | NOTUM (0.39) | KDM4EALDH1A1GAAHPGDNOTUM | |
| SCHEMBL27744187 | 0.73 | GPR17 (0.40) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL1044787 | 0.73 | NOTUM (0.41) | KDM4EALDH1A1GAAHPGDNOTUM | |
| SCHEMBL3105456 | 0.69 | NOTUM (0.39) | NOTUMGPR17DAOHCAR2 | |
| SCHEMBL6622235 | 0.69 | NOTUM (0.39) | KDM4EALDH1A1GAAHPGDNOTUM | |
| SCHEMBL3060385 | 0.69 | KDM4E (0.39) | KDM4EALDH1A1GAAHPGDNOTUM | |
| SCHEMBL3579630 | 0.67 | FABP3 (0.42) | NOTUMDAOHCAR2 | |
| SCHEMBL19350085 | 0.67 | ADORA1 (0.39) | GAANOTUMGPR35DAOHCAR2 | |
| SCHEMBL8740913 | 0.67 | ALDH1A1 (0.35) | KDM4EALDH1A1TP53GLAGAA | |
| SCHEMBL13813425 | 0.66 | SMN1; SMN2 (0.57) | KDM4EALDH1A1GAAHPGDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101412711-A | Carbamate derivatives and use thereof in medicine | SHANGHAI HENGRUI PHARM CO LTD (CN) | 2009-04-22 | — | — | CN | disclosed |