SCHEMBL6622235

SCHEMBL6622235

Cc1cc(C)c(C(=O)O)[nH]1.[CH2]C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 3/20 0.39
KDM4E B2RXH2 3/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
GAA P10253 1/20 0.38
ALDH1A1 P00352 4/20 0.37
DAO P14920 2/20 0.36
HCAR2 Q8TDS4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
GPR17 Q13304 1/20 0.35
MAPK1 P28482 1/20 0.34
RPA1 P27694 1/20 0.34
MCL1 Q07820 1/20 0.34
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
POLB P06746 1/20 0.33
PKM P14618 1/20 0.33
NPY1R P25929 1/20 0.33
NPY2R P49146 1/20 0.33
TPMT P51580 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1044787 0.96 NOTUM (0.41) NOTUMKDM4EHPGDHSD17B10GAA
SCHEMBL23758516 0.79 ALDH1A1 (0.40) NOTUMKDM4EHPGDHSD17B10GAA
SCHEMBL3728873 0.77 CYP1A2 (0.40) GAAALDH1A1L3MBTL1MAPK1MEN1
SCHEMBL4472003 0.76 ALOX15 (0.48) KDM4EHPGDHSD17B10GAAALDH1A1
SCHEMBL17883332 0.76 ALDH1A1 (0.38) ALDH1A1MAPK1POLBHTTMAPT
SCHEMBL15979650 0.74 ALDH1A1 (0.41) KDM4EGAAALDH1A1L3MBTL1GPR17
SCHEMBL3105456 0.74 NOTUM (0.39) NOTUMDAOHCAR2GPR17
SCHEMBL31386913 0.74 NOTUM (0.39) NOTUMKDM4EHPGDHSD17B10GAA
SCHEMBL3060385 0.74 KDM4E (0.39) NOTUMKDM4EHPGDHSD17B10GAA
SCHEMBL14157647 0.74 GPR35 (0.41) NOTUMKDM4EHPGDHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1152829-A4 CATALYST AND PROCESSES FOR OLEFIN TRIMERIZATION CONOCOPHILLIPS CO (US) 2004-06-16 EP disclosed
EP-1152829-A1 CATALYST AND PROCESSES FOR OLEFIN TRIMERIZATION Phillips Petroleum Company (US) 2001-11-14 EP disclosed
WO-2000037175-A1 CATALYST AND PROCESSES FOR OLEFIN TRIMERIZATION PHILLIPS PETROLEUM COMPANY (US) 2000-06-29 WO disclosed