Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 3/20 | 0.39 |
| ▸ | GCK | P35557 | 2/20 | 0.39 |
| ▸ | GCKR | Q14397 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 2/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL611676 | 0.83 | KDM4E (0.53) | TRPC6GCKGCKRPIK3CAMTOR | |
| SCHEMBL30664050 | 0.83 | KDM4E (0.53) | TRPC6GCKGCKRPIK3CAMTOR | |
| SCHEMBL27563955 | 0.80 | MAPT (0.53) | MAPTALDH1A1KDM4EPKMHRH3 | |
| SCHEMBL27765461 | 0.80 | TRPC6 (0.44) | TRPC6GCKGCKRMAPTALDH1A1 | |
| SCHEMBL27765218 | 0.79 | MAPT (0.60) | MAPTOGA | |
| SCHEMBL22813083 | 0.77 | TRPC6 (0.42) | TRPC6GCKGCKRPIK3CAMTOR | |
| SCHEMBL27833100 | 0.77 | HRH3 (0.43) | ALDH1A1KDM4EOGAHRH3 | |
| SCHEMBL2723372 | 0.77 | PIK3CA (0.42) | TRPC6GCKGCKRPIK3CAMTOR | |
| SCHEMBL29437380 | 0.77 | PIK3CA (0.42) | TRPC6GCKGCKRPIK3CAMTOR | |
| SCHEMBL29664444 | 0.75 | MAPT (0.58) | PIK3CAMTORMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101594871-B | Pyrrolopyrimidine compounds and their uses | NOVARTIS AG | 2013-06-19 | — | — | CN | disclosed |
| CN-101594871-A | Pyrrolopyrimidine compounds and uses thereof | NOVARTIS AG (CH) | 2009-12-02 | — | — | CN | disclosed |