Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL28962327 | 0.91 | LMNA (0.46) | LMNACA5ACA5BALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL6361862 | 0.89 | — | — | |
| Acrylic Acid SCHEMBL11143558 | 0.84 | LMNA (0.43) | LMNACA5ACA5BALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL29707305 | 0.84 | LMNA (0.71) | LMNAALOX15HSD17B10ALDH1A1TDP1 | |
| Acrylic Acid SCHEMBL11406925 | 0.84 | LMNA (0.71) | LMNAALOX15HSD17B10ALDH1A1TDP1 | |
| Acrylic Acid SCHEMBL15955850 | 0.84 | LMNA (0.71) | LMNAALOX15HSD17B10ALDH1A1TDP1 | |
| Acrylic Acid SCHEMBL36466 | 0.84 | — | — | |
| Acrylic Acid SCHEMBL2524668 | 0.84 | LMNA (0.71) | LMNAALOX15HSD17B10ALDH1A1TDP1 | |
| Acrylic Acid SCHEMBL29457256 | 0.84 | LMNA (0.71) | LMNAALOX15HSD17B10ALDH1A1TDP1 | |
| Acrylic Acid SCHEMBL25515 | 0.84 | LMNA (0.71) | LMNAALOX15HSD17B10ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541666-B | Fluid-permeable body having a superhydrophobic surface | LUCENT TECHNOLOGIES INC | 2012-03-28 | — | — | CN | disclosed |
| CN-101541666-A | Fluid-permeable body having a superhydrophobic surface | LUCENT TECHNOLOGIES INC (US) | 2009-09-23 | — | — | CN | disclosed |