Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL27765669 | 0.91 | LMNA (0.50) | LMNACA5ACA5BALOX15HSD17B10 | |
| Acrylic Acid SCHEMBL30721670 | 0.85 | LMNA (0.62) | LMNAALOX15HSD17B10ALDH1A1TDP1 | |
| Acrylic Acid SCHEMBL9116202 | 0.85 | LMNA (0.62) | LMNAALOX15HSD17B10ALDH1A1TDP1 | |
| Acrylic Acid SCHEMBL30876351 | 0.85 | LMNA (0.62) | LMNAALOX15HSD17B10ALDH1A1TDP1 | |
| Acrylic Acid SCHEMBL6361862 | 0.85 | — | — | |
| Acrylic Acid SCHEMBL29794133 | 0.85 | LMNA (0.62) | LMNAALOX15HSD17B10ALDH1A1TDP1 | |
| Acrylic Acid SCHEMBL1629116 | 0.85 | LMNA (0.62) | LMNAALOX15HSD17B10ALDH1A1TDP1 | |
| 1,6-Hexanediol SCHEMBL29398224 | 0.80 | LMNA (0.56) | LMNAALOX15HSD17B10ALDH1A1TDP1 | |
| Acrylic Acid SCHEMBL11143558 | 0.80 | LMNA (0.43) | LMNACA5ACA5BALOX15HSD17B10 | |
| 1,4-Butanediol SCHEMBL29620370 | 0.80 | LMNA (0.62) | LMNAALOX15HSD17B10ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427389-A | Process for the preparation of omega-alkanediol mononitrate | 帝斯曼知识产权资产管理有限公司 | 2022-12-02 | — | — | CN | disclosed |