⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615225 | 0.78 | TSHR (0.32) | — | |
| SCHEMBL5657511 | 0.74 | CYP11B1 (0.33) | — | |
| SCHEMBL730978 | 0.65 | — | — | |
| SCHEMBL7626872 | 0.63 | FDPS (0.41) | — | |
| SCHEMBL28327521 | 0.63 | CYP1A2 (0.31) | — | |
| SCHEMBL27432794 | 0.59 | ELANE (0.32) | — | |
| SCHEMBL29114576 | 0.59 | IDO1 (0.33) | — | |
| SCHEMBL28045390 | 0.59 | FDPS (0.34) | — | |
| Bromide SCHEMBL28907518 | 0.58 | FDPS (0.33) | — | |
| SCHEMBL28183764 | 0.58 | FDPS (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101421273-B | Spiro-imidazo compounds | SPEEDEL EXPERIMENTA AG (CH) | 2012-02-15 | — | — | CN | disclosed |
| CN-101421273-A | Spiro-imidazo compounds | SPEEDEL EXPERIMENTA AG (CH) | 2009-04-29 | — | — | CN | disclosed |