SCHEMBL28615225

SCHEMBL28615225

CC(=O)On1cncc1C

nearest known ligand 0.40

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28327521 0.84 CYP1A2 (0.31)
SCHEMBL27432794 0.79 ELANE (0.32)
SCHEMBL27765670 0.78
SCHEMBL5657511 0.76 CYP11B1 (0.33)
SCHEMBL9639870 0.68
SCHEMBL27843880 0.66 TSHR (0.32) TSHR
SCHEMBL3147962 0.65 ALDH1A1 (0.34) TSHR
SCHEMBL7626872 0.65 FDPS (0.41) TSHR
SCHEMBL27393592 0.64 TSHR (0.32) TSHR
SCHEMBL28045390 0.64 FDPS (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106999479-B Heteroaryl compounds useful as inhibitors of SUMO activating enzyme 米伦纽姆医药公司 2021-07-16 CN disclosed