SCHEMBL2776583

SCHEMBL2776583

O=C(O)c1ccccc1N(O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
ALOX15 P16050 1/20 0.59
SMN1; SMN2 Q16637 2/20 0.50
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA4 P22748 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
NAPRT Q6XQN6 2/20 0.50
KDM4E B2RXH2 1/20 0.50
HMGB1 P09429 1/20 0.50
HPGD P15428 1/20 0.50
CA6 P23280 1/20 0.50
CA14 Q9ULX7 1/20 0.50
MAPT P10636 3/20 0.48
HDAC8 Q9BY41 1/20 0.48
POLB P06746 1/20 0.46
AKR1C3 P42330 1/20 0.46
NR4A1 P22736 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13066508 0.83 ALDH1A1 (0.62) ALDH1A1ALOX15SMN1; SMN2CA12CA1
SCHEMBL14100191 0.80 ALDH1A1 (0.53) ALDH1A1ALOX15SMN1; SMN2CA12CA1
SCHEMBL10834328 0.80 ALDH1A1 (0.52) ALDH1A1ALOX15SMN1; SMN2CA12CA1
SCHEMBL10820293 0.80 ALDH1A1 (0.46) ALDH1A1ALOX15SMN1; SMN2CA12CA1
SCHEMBL972143 0.79 ALDH1A1 (0.56) ALDH1A1ALOX15SMN1; SMN2CA12CA1
SCHEMBL14893324 0.79 ALDH1A1 (0.56) ALDH1A1ALOX15SMN1; SMN2CA12CA1
SCHEMBL9163281 0.79 ALDH1A1 (0.56) ALDH1A1ALOX15SMN1; SMN2CA12CA1
SCHEMBL4070091 0.79 ALDH1A1 (0.56) ALDH1A1ALOX15SMN1; SMN2CA12CA1
SCHEMBL18158039 0.79 ALDH1A1 (0.56) ALDH1A1ALOX15SMN1; SMN2CA12CA1
SCHEMBL7064355 0.79 ALDH1A1 (0.56) ALDH1A1ALOX15SMN1; SMN2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010141883-A1 COMPOUNDS THAT MODULATE AUTOIMMUNITY AND METHODS OF USING THE SAME THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2010-12-09 WO claimed
WO-2014014590-A1 HIGH GLASS TRANSITION TEMPERATURE THERMOSET AND METHOD OF MAKING THE SAME BAKER HUGHES INCORPORATED (US) 2014-01-23 WO disclosed