SCHEMBL4070091

SCHEMBL4070091

O=C(O)c1ccccc1N(Cl)Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
ALOX15 P16050 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.48
KDM4E B2RXH2 2/20 0.48
HPGD P15428 2/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
HMGB1 P09429 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
CA14 Q9ULX7 1/20 0.48
PTPN1 P18031 8/20 0.47
MAPT P10636 2/20 0.46
HDAC8 Q9BY41 1/20 0.46
POLB P06746 1/20 0.45
AKR1C3 P42330 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14718826 0.83 ALDH1A1 (0.52) ALDH1A1ALOX15SMN1; SMN2KDM4EHPGD
SCHEMBL30927812 0.83 ALDH1A1 (0.52) ALDH1A1ALOX15SMN1; SMN2KDM4EHPGD
SCHEMBL13066508 0.81 ALDH1A1 (0.62) ALDH1A1ALOX15SMN1; SMN2KDM4EHPGD
SCHEMBL4249097 0.81 ALDH1A1 (0.50) ALDH1A1ALOX15SMN1; SMN2KDM4EHPGD
SCHEMBL10431860 0.79 ALDH1A1 (0.48) ALDH1A1ALOX15SMN1; SMN2KDM4EHPGD
SCHEMBL10743844 0.79 AKR1C3 (0.48) ALDH1A1ALOX15SMN1; SMN2KDM4EHPGD
SCHEMBL2776583 0.79 ALDH1A1 (0.59) ALDH1A1ALOX15SMN1; SMN2KDM4EHPGD
SCHEMBL9163281 0.77 ALDH1A1 (0.56) ALDH1A1ALOX15SMN1; SMN2KDM4EHPGD
SCHEMBL7064355 0.77 ALDH1A1 (0.56) ALDH1A1ALOX15SMN1; SMN2KDM4EHPGD
SCHEMBL14893324 0.77 ALDH1A1 (0.56) ALDH1A1ALOX15SMN1; SMN2KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4996339-A Colorless ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1991-02-26 US claimed
US-3931300-A Process for the production of dichlorobenzoic acids BASF AKTIENGESELLSCHAFT (DT) 1976-01-06 US claimed
CN-114801375-A Insect-proof heat-insulation fabric and preparation method thereof 盛建浩 2022-07-29 CN disclosed
CN-111004128-A Production process of 3, 5-dichloroaniline 宁波巨化化工科技有限公司 2020-04-14 CN disclosed
CN-103857666-B N-thio-anthranilamide compounds and their use as pesticides 巴斯夫欧洲公司 2016-12-14 CN disclosed
CN-105906502-A Preparation method of 3,5-dichlorobenzoyl chloride 山东润博生物科技有限公司 2016-08-31 CN disclosed
CN-105837432-A Novel preparation method of 3,5-dichlorobenzoyl chloride 山东润博生物科技有限公司 2016-08-10 CN disclosed
CN-104016855-B Synthesis method of 3,5-dichlorobenzoyl chloride JIANGXI JIXIANG PHARMACEUTICAL CO LTD 2015-06-24 CN disclosed
CN-103508880-B Method for synthesizing 3,5-dichlorobenzoyl chloride JIANGXI JIXIANG PHARMACEUTICAL CO LTD 2015-03-11 CN disclosed
EP-2035406-A4 NOVEL SUBSTITUTED-1H-QUINAZOLINE-2,4-DIONE DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME KOREA RES INST CHEM TECH (KR) 2009-08-05 EP disclosed
EP-2035406-A1 NOVEL SUBSTITUTED-1H-QUINAZOLINE-2,4-DIONE DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME Korea Research Institute of Chemical Technology (KR) 2009-03-18 EP disclosed
WO-2008004716-A1 NOVEL SUBSTITUTED-1H-QUINAZOLINE-2,4-DIONE DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME KOREA RESERACH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2008-01-10 WO disclosed
US-4418038-A Disinfecting with chlorine-containing biocide dispensed from shaped polymeric body ALZA CORPORATION (US) 1983-11-29 US disclosed
US-4355127-A Physical property improvement in nitrile resins by use of certain processing aids and fillers SOHIO (US) 1982-10-19 US disclosed
US-4292228-A MOLDING MATERIALS COMPRISING A NITRILE-ESTER-CONJUGATED DIENE ADDITION POLYMER, AN ANHYDRIDE, AND AN INORGANIC COMPOUND THE STANDARD OIL COMPANY (US) 1981-09-29 US disclosed
US-3931300-A Process for the production of dichlorobenzoic acids BASF AKTIENGESELLSCHAFT (DT) 1976-01-06 US disclosed
US-3931300-A Process for the production of dichlorobenzoic acids BASF AKTIENGESELLSCHAFT (DT) 1976-01-06 US disclosed