Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CCR1 | P32246 | 3/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | GPR6 | P46095 | 5/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774697 | 0.90 | CCR1 (0.49) | CCR1GPR6 | |
| SCHEMBL2776203 | 0.90 | CCR1 (0.49) | KMT2ACCR1LMNATSHREPHX2 | |
| SCHEMBL2776919 | 0.89 | CCR1 (0.48) | KMT2ACCR1LMNATSHRGPR6 | |
| SCHEMBL2773855 | 0.88 | CCR1 (0.48) | KMT2ACCR1LMNATSHRGPR6 | |
| SCHEMBL2777958 | 0.86 | CCR1 (0.47) | KMT2ACCR1 | |
| SCHEMBL2775382 | 0.85 | CCR1 (0.46) | KMT2ACCR1LMNATSHREPHX2 | |
| SCHEMBL2775871 | 0.85 | PTGDR (0.46) | KMT2ACCR1PDE4BLMNATSHR | |
| SCHEMBL2779822 | 0.83 | CCR1 (0.46) | KMT2ACCR1LMNATSHRGPR6 | |
| SCHEMBL2774930 | 0.83 | CCR1 (0.43) | KMT2ACCR1LMNATSHRGPR6 | |
| SCHEMBL2775803 | 0.83 | CCR1 (0.55) | KMT2ACCR1LMNATSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |