Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 12/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776203 | 0.85 | CCR1 (0.49) | CCR1KMT2ALMNATSHRGPR6 | |
| SCHEMBL2774697 | 0.85 | CCR1 (0.49) | CCR1KCNH2GPR6 | |
| SCHEMBL2776919 | 0.84 | CCR1 (0.48) | CCR1KMT2ALMNATSHRKCNH2 | |
| SCHEMBL2776593 | 0.83 | KMT2A (0.50) | CCR1KMT2ALMNATSHRGPR6 | |
| SCHEMBL2773855 | 0.83 | CCR1 (0.48) | CCR1KMT2ALMNATSHRKCNH2 | |
| SCHEMBL6524519 | 0.81 | CCR1 (0.37) | CCR1GPR6 | |
| SCHEMBL2775382 | 0.80 | CCR1 (0.46) | CCR1KMT2ALMNATSHRKCNH2 | |
| SCHEMBL2777958 | 0.79 | CCR1 (0.47) | CCR1KMT2A | |
| SCHEMBL2774930 | 0.78 | CCR1 (0.43) | CCR1KMT2ALMNATSHRGPR6 | |
| SCHEMBL2775871 | 0.78 | PTGDR (0.46) | CCR1KMT2ALMNATSHRGPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |