Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 11/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776593 | 0.86 | KMT2A (0.50) | CCR1KMT2A | |
| SCHEMBL2774697 | 0.84 | CCR1 (0.49) | CCR1 | |
| SCHEMBL2776203 | 0.84 | CCR1 (0.49) | CCR1KMT2A | |
| SCHEMBL2776919 | 0.83 | CCR1 (0.48) | CCR1KMT2A | |
| SCHEMBL2773855 | 0.82 | CCR1 (0.48) | CCR1KMT2A | |
| SCHEMBL6522508 | 0.81 | HTR2C (0.42) | HTR2CHTR2BACACBPARP1 | |
| SCHEMBL2775382 | 0.80 | CCR1 (0.46) | CCR1KMT2A | |
| SCHEMBL2779822 | 0.79 | CCR1 (0.46) | CCR1KMT2A | |
| SCHEMBL2775871 | 0.79 | PTGDR (0.46) | CCR1KMT2A | |
| SCHEMBL2779054 | 0.79 | CCR1 (0.43) | CCR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |