Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1915348 | 0.78 | CTSS (0.51) | CTSSCTSKSLC1A1SLC7A5PPARG | |
| SCHEMBL1915346 | 0.78 | CTSS (0.51) | CTSSCTSKSLC1A1SLC7A5PPARG | |
| SCHEMBL27745166 | 0.78 | CYP3A4 (0.41) | PPARGPPARAALDH1A1NPSR1LMNA | |
| SCHEMBL30475895 | 0.76 | SLC7A5 (0.55) | CTSSCTSKSLC1A1SLC7A5PPARG | |
| SCHEMBL10561439 | 0.76 | SLC7A5 (0.55) | CTSSCTSKSLC1A1SLC7A5PPARG | |
| SCHEMBL19664048 | 0.76 | SLC7A5 (0.55) | CTSSCTSKSLC1A1SLC7A5PPARG | |
| SCHEMBL27962918 | 0.76 | CTSS (0.47) | CTSSCTSKSLC1A1SLC7A5PPARG | |
| SCHEMBL27962912 | 0.76 | CTSS (0.47) | CTSSCTSKSLC1A1SLC7A5PPARG | |
| SCHEMBL27610061 | 0.74 | CTSS (0.52) | CTSSCTSKSLC1A1SLC7A5PPARG | |
| SCHEMBL1519838 | 0.73 | CPA1 (0.60) | CTSSCTSKATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101460461-A | Process for preparation of enantiomerically enriched cyclic beta-aryl or heteroaryl carboxylic acids | HOFFMANN LA ROCHE (CH) | 2009-06-17 | — | — | CN | claimed |
| CN-101460461-A | Process for preparation of enantiomerically enriched cyclic beta-aryl or heteroaryl carboxylic acids | HOFFMANN LA ROCHE (CH) | 2009-06-17 | — | — | CN | disclosed |