Ethylene Glycol

Ethylene Glycol

SCHEMBL277666

CC1OC(=O)C(C)OC1=O.OCCO

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
GBA1 P04062 1/20 0.33
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PPARG P37231 2/20 0.31
MANBA O00462 1/20 0.30
THRB P10828 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL15069810 1.00 LMNA (0.33) LMNAGBA1CA1CA9MEN1
Ethylene Glycol SCHEMBL29359239 1.00 LMNA (0.33) LMNAGBA1CA1CA9MEN1
Alcohol SCHEMBL9222989 0.89 LMNA (0.33) LMNAGBA1CA1CA9MEN1
SCHEMBL15034 0.85 CA1 (0.41) CA1CA9MEN1KMT2ASMN1; SMN2
SCHEMBL439067 0.85 CA1 (0.41) CA1CA9MEN1KMT2ASMN1; SMN2
SCHEMBL44996 0.85 CA1 (0.41) CA1CA9MEN1KMT2ASMN1; SMN2
SCHEMBL8104271 0.85 CA1 (0.41) CA1CA9MEN1KMT2ASMN1; SMN2
SCHEMBL2860232 0.85 CA1 (0.41) CA1CA9MEN1KMT2ASMN1; SMN2
SCHEMBL15195848 0.85 CA1 (0.41) CA1CA9MEN1KMT2ASMN1; SMN2
SCHEMBL732959 0.85 CA1 (0.41) CA1CA9MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220401538-A1 THERAPEUTIC MRNA VACCINE FOR MALIGNANCIES ONCOCINE, LLC 2022-12-22 US claimed
CN-112955513-A Solvent-free marine antifouling paint and preparation method thereof 厦门双瑞船舶涂料有限公司 2021-06-11 CN claimed
US-20210045414-A1 PROCESS OF PRODUCING ALPHA-HYDROXY COMPOUNDS AND USES THEREOF HALDOR TOPSØE A/S (DK) 2021-02-18 US claimed
EP-3749635-A1 PROCESS OF PRODUCING ALPHA-HYDROXY COMPOUNDS AND USES THEREOF Haldor Topsøe A/S (DK) 2020-12-16 EP claimed
CN-110511328-B Branched-point-breaking type hyperbranched resin and preparation method and application thereof 华南理工大学 2020-11-24 CN claimed
WO-2019154624-A1 PROCESS OF PRODUCING ALPHA-HYDROXY COMPOUNDS AND USES THEREOF HALDOR TOPSØE A/S (DK) 2019-08-15 WO claimed
US-20180140662-A1 Sustained Release Formulation Comprising Octreotide and Two or More Polylactide-co-glycolide Polymers NOVARTIS AG (CH) 2018-05-24 US claimed
CN-104710576-B Thermotropic crosslinking type shape memory polyurethane material and preparation method thereof 四川大学 2017-04-19 CN claimed
CN-118291027-A Environment-friendly ship antifouling paint suitable for long-term fresh water/fresh sea water outfitting, and preparation method and use method thereof 厦门双瑞船舶涂料有限公司 2024-07-05 CN disclosed
CN-117757236-A Degradable material, preparation method and application 杭州糖吉医疗科技有限公司 2024-03-26 CN disclosed
US-11844837-B2 Compositions of a polyorthoester and an organic acid excipient HERON THERAPEUTICS, INC. (US) 2023-12-19 US disclosed
EP-3033113-B1 A NOVEL PLGA-MODIFIED POLYETHYLENIMINE SELF-ASSEMBLY NANOTECHNOLOGY FOR NUCLEIC ACID AND DRUG DELIVERY BAYLOR COLLEGE MEDICINE (US) 2023-10-04 EP disclosed
US-11613609-B2 PLGA-modified polyethylenimine self-assembly nanotechnology for nucleic acid and drug delivery BAYLOR COLLEGE OF MEDICINE (US) 2023-03-28 US disclosed
US-20220401538-A1 THERAPEUTIC MRNA VACCINE FOR MALIGNANCIES ONCOCINE, LLC 2022-12-22 US disclosed
WO-2002041844-A9 CHEMOTHERAPEUTIC COMPOSITION USING NANOCRYSTALLINE CALCIUM PHOSPHATE PASTE ETEX CORP (US) 2003-05-22 WO disclosed
WO-2002065981-A2 CHEMOTHERAPEUTIC COMPOSITION USING CALCIUM PHOSPHATE PASTE ETEX CORPORATION (US) 2002-08-29 WO disclosed
WO-2002041844-A2 CHEMOTHERAPEUTIC COMPOSITION USING NANOCRYSTALLINE CALCIUM PHOSPHATE PASTE ETEX CORPORATION (US) 2002-05-30 WO disclosed
US-5277900-A Applying a wax of hydroxycarboxylic acid HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1994-01-11 US disclosed
US-4155992-A SUSTAINED RELEASE ALZA CORPORATION (US) 1979-05-22 US disclosed
US-4070347-A Poly(orthoester) co- and homopolymers and poly(orthocarbonate) co- and homopolymers having carbonyloxy functionality ALZA CORPORATION (US) 1978-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11844837-B2 Compositions of a polyorthoester and an organic acid excipient OTC, OAT, SLCO2A1 LMNA 3136/4885GBA1 1245/4885CA1 831/4885
US-20210045414-A1 PROCESS OF PRODUCING ALPHA-HYDROXY COMPOUNDS AND USES THEREOF HAAO, CYP8B1, PAH LMNA 2819/4885GBA1 2350/4885CA1 4182/4885
US-20180140662-A1 Sustained Release Formulation Comprising Octreotide and Two or More Polylactide-co-glycolide Polymers SSTR2, SSTR4, SSTR3 LMNA 3501/4885GBA1 772/4885CA1 1664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.