Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27879729 | 0.88 | MEN1 (0.72) | HTR6MEN1KMT2AL3MBTL1HTT | |
| SCHEMBL3363510 | 0.79 | MEN1 (0.56) | HTR6MEN1KMT2AL3MBTL1HTT | |
| SCHEMBL28763884 | 0.78 | HTR6 (0.59) | HTR6MEN1KMT2AL3MBTL1HDAC1 | |
| SCHEMBL3145438 | 0.78 | MEN1 (0.54) | HTR6MEN1KMT2AL3MBTL1PKM | |
| SCHEMBL3363606 | 0.75 | HTR6 (0.56) | HTR6MEN1KMT2AL3MBTL1HDAC1 | |
| SCHEMBL2573218 | 0.75 | MEN1 (0.60) | HTR6MEN1KMT2AL3MBTL1PKM | |
| SCHEMBL29408218 | 0.75 | MEN1 (0.60) | HTR6MEN1KMT2AL3MBTL1PKM | |
| SCHEMBL31159555 | 0.74 | HTR6 (0.76) | HTR6MEN1KMT2AL3MBTL1PKM | |
| SCHEMBL945665 | 0.74 | HTR6 (0.76) | HTR6MEN1KMT2AL3MBTL1PKM | |
| SCHEMBL3363394 | 0.73 | HTR6 (0.52) | HTR6MEN1KMT2APKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101605759-A | 1-benzenesulfonyl-1H-indole derivatives as inhibitors of CCR9 activity | NOVARTIS AG (CH) | 2009-12-16 | — | — | CN | disclosed |