Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3363510 | 0.90 | MEN1 (0.56) | HTR6MEN1KMT2AFABP4HDAC1 | |
| SCHEMBL28763884 | 0.87 | HTR6 (0.59) | HTR6MEN1KMT2AFABP4HDAC1 | |
| SCHEMBL3146265 | 0.82 | HTR6 (0.47) | HTR6MEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL3133305 | 0.79 | CPT1A (0.54) | HTR6MEN1KMT2AFABP4HDAC1 | |
| SCHEMBL18161364 | 0.75 | HTR6 (0.49) | HTR6MEN1KMT2AFABP4SLC1A3 | |
| SCHEMBL27766601 | 0.75 | HTR6 (0.56) | HTR6MEN1KMT2AFABP4HDAC1 | |
| SCHEMBL27879729 | 0.75 | MEN1 (0.72) | HTR6MEN1KMT2AFABP4HDAC1 | |
| SCHEMBL3141559 | 0.74 | HDAC6 (0.49) | HTR6MEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL19475867 | 0.74 | HTR6 (0.48) | HTR6MEN1KMT2AFABP4SLC1A3 | |
| SCHEMBL3140526 | 0.74 | HTR6 (0.45) | HTR6MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118060-B1 | 1-BENZENESULFONYL-1H-INDOLE DERIVATIVES AS INHIBITORS OF CCR9 ACTIVITY | NOVARTIS AG (CH) | 2010-10-06 | — | — | EP | claimed |