Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 4/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 3/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27788241 | 0.84 | TYMS (0.47) | TYMSNCEH1THRBTHRAEP300 | |
| SCHEMBL27766457 | 0.80 | NCEH1 (0.46) | TYMSNCEH1THRBTHRAPKM | |
| SCHEMBL3291662 | 0.76 | THRB (0.49) | TYMSTHRBTHRAHSD17B10KDM4E | |
| SCHEMBL10720203 | 0.76 | TYMS (0.56) | TYMSNCEH1THRBTHRAPKM | |
| SCHEMBL27766752 | 0.75 | ALDH1A1 (0.41) | TYMSTHRBHSD17B10KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL27850048 | 0.75 | THRB (0.48) | TYMSTHRBTHRAHSD17B10KDM4E | |
| SCHEMBL30226855 | 0.74 | HTT (0.41) | TYMSNCEH1THRBTHRAPKM | |
| SCHEMBL29413361 | 0.73 | THRB (0.56) | TYMSTHRBTHRAPKMHSD17B10 | |
| SCHEMBL3841280 | 0.73 | THRB (0.56) | TYMSTHRBTHRAPKMHSD17B10 | |
| SCHEMBL30342255 | 0.72 | TYMS (0.56) | TYMSTHRBTHRAHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101617251-A | Blooming | SUMITOMO CHEMICAL CO | 2009-12-30 | — | — | CN | disclosed |