Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29016737 | 0.86 | NOS2 (0.35) | — | |
| SCHEMBL2143933 | 0.79 | KDM4E (0.33) | — | |
| SCHEMBL7262842 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL9623702 | 0.77 | SLC22A6 (0.33) | — | |
| Hydrochloric Acid SCHEMBL28497347 | 0.77 | SLC22A6 (0.33) | — | |
| SCHEMBL27502205 | 0.77 | PDE5A (0.33) | — | |
| SCHEMBL1509564 | 0.76 | — | — | |
| SCHEMBL29092928 | 0.76 | — | — | |
| SCHEMBL4605821 | 0.75 | ALDH1A1 (0.40) | ALOX15 | |
| SCHEMBL6602546 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101605777-A | Imidazoles as aldosterone synthase inhibitors | NOVARTIS AG (CH) | 2009-12-16 | — | — | CN | disclosed |